Quote Sherlock Holmes
They're dangerous at both ends and... crafty in the middle. Why would I want anything with a mind of its own bobbing about between my legs?
Synopsis
Detective Sherlock Holmes is on the trail of criminal mastermind professor Moriarty, who is carrying out a string of random crimes across Europe.
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Storyline
With Dr. John Watson about to marry and end their partnership, a disconsolate Sherlock Holmes occupies his time investigating the schemes of his archenemy, Professor James Moriarty. However, when Moriarty warns that he considers the Watsons a legitimate target for his retaliation against the detective, Holmes must save them and get John involved in one last case.
To do so, they join the Roma lady Madam Simza Heron's quest to find her missing brother, Renee, who may be the key to defeating Moriarty. Together, the trio find themselves involved in a dangerous international conspiracy led by the Napoleon of Crime in which the fate of all of Europe hangs in the balance.

Did you know?
Warner Bros spent about $1 million for the shooting of the opening sequence in Strasbourg (France). Only 3 shots were edited in the movie. 23 seconds for the opening scene and 13 seconds under a porch at about 52 minutes.
Holmes